Duplication 15q11-q13 Syndrome

Autosomal dominant abnormalities of chromosome 15q: features of the chromosome 15q11-q13 duplication syndrome include AUTISM SPECTRUM DISORDER; INTELLECTUAL DISABILITY; ATAXIA, seizures, developmental delays, and behavioral problems. OMIM: 608636. A heterozygous deletion of chromosome 15q11.2 may increase the susceptibility to neuropsychiatric or neurodevelopmental problems, including delayed psychomotor development, speech delay, ATTENTION DEFICIT-HYPERACTIVITY DISORDER; OBSESSIVE-COMPULSIVE DISORDER, and possibly seizures. OMIM: 615656

Also Known As:

15q11.2 microdeletion; Chromosome 15q11-q13 Duplication Syndrome; Chromosome 15q11.2 deletion syndrome; Microdeletion 15q11.2

Signs and Symptoms Pathological Conditions
- Pathologic Processes: 10385
  - Chromosome Aberrations: 11465
    - Duplication 15q11-q13 Syndrome: 3
- Signs and Symptoms
  - Neurologic Manifestations: 7223
    - Neurobehavioral Manifestations: 1632
      - Intellectual Disability: 8222
        Duplication 15q11-q13 Syndrome: 3
Genetic Phenomena
- Genetic Structures
  - Chromosomes
    - Mammalian Chromosomes
      - Human Chromosomes
        13-15 Human Chromosomes
        Pair 15 Human Chromosomes
        Duplication 15q11-q13 Syndrome: 3
- Genetic Variation
  - Mutation
    - Chromosome Aberrations: 11465
      - Duplication 15q11-q13 Syndrome: 3
Cells
- Cellular Structures
  - Chromosomes
    - Mammalian Chromosomes
      - Human Chromosomes
        13-15 Human Chromosomes
        Pair 15 Human Chromosomes
        Duplication 15q11-q13 Syndrome: 3
Nervous System Diseases: 14737
- Neurologic Manifestations: 7223
  - Neurobehavioral Manifestations: 1632
    - Intellectual Disability: 8222
      - Duplication 15q11-q13 Syndrome: 3
Behavior and Behavior Mechanisms
- Neurobehavioral Manifestations: 1632
  - Intellectual Disability: 8222
    - Duplication 15q11-q13 Syndrome: 3
Mental Disorders: 25040
- Neurodevelopmental Disorders: 3318
  - Intellectual Disability: 8222
    - Duplication 15q11-q13 Syndrome: 3

Mandakini Singh Selected Research

Mandakini Singh Research Topics

Disease

Drug/Important Bio-Agent (IBA)